Microfluidics: Technologies and Global Markets

Microfluidics is a set of technologies that deal with the movement of small amounts of fluid. The field has been developing for more than two decades, but most of the early development, while intense, was in isolated modules. More recently, scientists have been putting the pieces together into systems, leading to new applications and rapid market growth.

This report covers the major markets and applications for microfluidics-based products and technologies. The current state of the market as defined is assessed, and projections for growth and advancements in technology along with market trends are detailed.

The major objectives of this report are:

• To provide a thorough evaluation of the technical and business environment surrounding the emerging microfluidic systems market.

• To review the technologies, the related sub-technologies and alternative technologies in light of the emerging needs of the relevant markets.

• To examine the current and potential applications of microfluidic technologies and assess their importance in the context of emerging market paradigms.

• To describe the spectrum of microfluidics-related products currently on the market and in development.

• To provide an overview of the current microfluidics market in terms of scale and competitive structure.

• To assess the future of the microfluidics market in terms of growth potential for various product and application segments.

• To examine the trends that will shape the future of microfluidics technologies and markets, and to examine their impacts.

The report is intended especially for entrepreneurs, investors, venture capitalists and other readers with a need to know where the microfluidics market is headed in the next five years. Other readers who should find the report particularly valuable include MEMS marketing executives and government officials associated with the National Nanotechnology Initiative and other state-level programs to promote the development of the nanotechnology injury. The report’s findings and conclusions should also be of interest to the broader nanotechnology community.

This report addresses the global market for microfluidics devices and applications, from 2011 (base year) through 2017. Microfluidic devices are defined, in general terms, as devices that handle very small (e.g., micro- or nanoliter) volumes of fluids.

The study format includes the following major elements:

• Executive summary.
• Definitions.
• Microfluidic components and systems.
• Microfluidic fabrication technologies
• Major end-user markets and applications.
• Global microfluidic market trends, 2011–2017.
• Industry structure, market shares and ownership trends.
• Factors that will influence the long-term development of microfluidic technologies.

METHODOLOGY AND INFORMATION SOURCES

Projecting the market for emerging technologies such as microfluidic technologies, whose commercial potential has not yet been proven, is a challenging task. This report uses a multi-phase approach to identify the technologies with the greatest commercial potential and quantify the market for these applications, as described below.

In the first phase of the analysis, we identified a “long list” of microfluidic technologies (including technologies that are still under development) and mapped them against potential applications and end-user industries, such as life sciences research, drug discovery and medical diagnostics.

In the second phase, we eliminated those technologies that appear to have little likelihood of making it into commercial production in the next five years, through a literature review and statements by industry sources. The result of phase two was a “short list” of technologies and applications with the greatest near- to mid-term commercial potential.

The third phase focused on quantifying the potential market for each short-listed technology and application and identifying the main prerequisites for commercial success. Various methodologies and data sources were used to develop the market projections, including trend line projections, input-output analysis and estimates of future demand from industry sources.

TABLE OF CONTENTS

Chapter 1: INTRODUCTION

STUDY GOALS AND OBJECTIVES

REASONS FOR DOING THE STUDY

INTENDED AUDIENCE

SCOPE AND FORMAT

METHODOLOGY AND INFORMATION SOURCES

AUTHOR'S CREDENTIALS

DISCLAIMER
 

Chapter 2: SUMMARY

 Table Summary : GLOBAL MARKET FORECAST FOR MICROFLUIDIC TECHNOLOGIES, THROUGH 2017
 Figure Summary : GLOBAL MARKET FOR MICROFLUIDIC TECHNOLOGIES, 2011–2017
 

Chapter 3: OVERVIEW

DEFINITIONS
MICROFLUIDICS

MEMS

BASIC CONCEPTS IN MICROFLUIDICS
GENERAL

WHAT IS A MICROFLUIDIC DEVICE?

BASIC PRINCIPLES OF MICROFLUIDICS

FINITE ELEMENT MODELING IN FLUID MECHANICS

SURFACE CHEMISTRY

DIFFUSION BONDING

"MICROJAWS" FOR GENETIC ENGINEERING AND THERAPEUTICS


MICROFLUIDIC COMPONENTS
TYPES OF MICROFLUIDIC COMPONENTS


MICROFLUIDIC SYSTEMS

FABRICATION OF MICROFLUIDIC COMPONENTS AND SYSTEMS
SENSORS

ACTUATORS

MICROSTRUCTURES

MICROSYSTEMS

MICROMACHINING


FEATURES OF MICROSYSTEMS
HYBRID MICROSYSTEMS

CORIOLIS MASS FLOW TECHNOLOGY

MATERIALS OF CONSTRUCTION

RELATED TECHNOLOGY CONSIDERATIONS


MAJOR END-USER MARKETS
HIGH-THROUGHPUT SCREENING (HTS) AND COMPOUND PROFILING

DIAGNOSTIC AND POINT-OF-CARE (POC)

INKJET PRINTING

CHEMICAL ANALYSIS

DRUG DELIVERY/MEDICAL

PROTEOMICS

DEFENSE AND PUBLIC SAFETY
 

Chapter 4: MICROFLUIDIC MARKET BY END-USER SEGMENTS

OVERVIEW
 Table 4 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC TECHNOLOGIES, THROUGH 2017
 Figure 4 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC TECHNOLOGIES, 2011–2017

HIGH-THROUGHPUT SCREENING AND COMPOUND PROFILING
INTRODUCTION

APPLICATIONS

MARKET FORECAST

MAJOR MANUFACTURERS AND MARKET SHARES


CLINICAL DIAGNOSTICS/POC TESTING
OVERVIEW

APPLICATIONS

MARKET FORECAST

MAJOR MANUFACTURERS AND MARKET SHARES


INKJET PRINTING
OVERVIEW

APPLICATIONS

MARKET FORECAST

MANUFACTURERS AND MARKET SHARES


CHEMICAL ANALYSIS AND SYNTHESIS
OVERVIEW

APPLICATIONS

MARKET FORECAST

MANUFACTURERS


DRUG DELIVERY/MEDICAL APPLICATIONS
OVERVIEW

APPLICATIONS

MARKET FORECAST

MANUFACTURERS AND MARKET SHARES


PROTEOMICS
OVERVIEW

APPLICATIONS

MARKET FORECAST

MANUFACTURERS AND MARKET SHARES


DEFENSE AND PUBLIC SAFETY
OVERVIEW

APPLICATIONS

MARKET FORECAST


OTHER
DISPENSING

NEW APPLICATIONS


Chapter 5: MICROFLUIDICS COMPANIES

AGILENT TECHNOLOGIES

CALIPER LIFE SCIENCES

CEPHEID

EKSIGENT TECHNOLOGIES

FLUIDIGM

GAMIDOR DIAGNOSTICS LTD.

GYROS MICROLABS

HEWLETT-PACKARD

INTELLIGENT MICRO PATTERNING LLC

INTELLISENSE SOFTWARE

MICRALYNE INC.

MICROCHIPS

MICROFLUIDIC SYSTEMS INC.

MICRONICS

ORCHID CELLMARK

SRU BIOSYSTEMS

TECAN

 Table 21 : MICROFLUIDICS COMPANIES
 

Chapter 6: MICROFLUIDICS DEALS

INTELLECTUAL PROPERTY CONSIDERATIONS

RECENT DEALS
NOTABLE DEALS BY YEAR

 Table 22 : SELECTED MICROFLUIDICS-RELATED DEALS, 1999-2011


Chapter 7: PATENT LANDSCAPE (DEVELOPMENTS SINCE 1999)

INTRODUCTION
TRENDS BY COUNTRY

TRENDS BY ASSIGNEE

TRENDS BY EMPHASIS: PRODUCTION VERSUS APPLICATION


Chapter 8: CHALLENGES AND TRENDS IN THE MICROFLUIDICS INDUSTRY

TECHNICAL CHALLENGES AND DEVELOPMENTS

MICROFLUIDICS AND NANOTECHNOLOGY


List of Tables

Summary Table : GLOBAL MARKET FORECAST FOR MICROFLUIDIC TECHNOLOGIES, THROUGH 2017
Table 1 : DESIGN OF MICROFLUIDIC DEVICES: PHASE PHENOMENA CONSIDERATIONS
Table 2 : DESIGN OF MICROFLUIDIC DEVICES: ACTUATION PRINCIPLES AND APPLICATIONS
Table 3 : FABRICATION TECHNIQUES FOR MICROFLUIDIC DEVICES
Table 4 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC TECHNOLOGIES, THROUGH 2017
Table 5 : GLOBAL MARKET FOR MICROFLUIDIC DEVICES IN HTS/COMPOUND SCREENING, THROUGH 2017
Table 6 : HTS/COMPOUND PROFILING COMPANIES, GLOBAL MARKET SHARE, 2011
Table 7 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC MEMS IN POC DIAGNOSTIC DEVICES, THROUGH 2017
Table 8 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC INKJET HEADS BY APPLICATION, THROUGH 2017
Table 9 : MARKET FORECAST FOR DISPOSABLE INKJET CARTRIDGE SHIPMENTS, THROUGH 2017
Table 10 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC INKJET PRINTER HEADS, THROUGH 2017
Table 11 : GLOBAL MARKET FORECAST FOR BIOCHIP SHIPMENTS, THROUGH 2017
Table 12 : GLOBAL MARKET FOR MICROFLUIDIC MEMS USED IN BIOCHIP PRODUCTION, THROUGH 2017
Table 13 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC MEMS USED IN FLAT PANEL DISPLAY PRODUCTION, THROUGH 2017
Table 14 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC MEMS USED IN PRODUCTION OF OTHER PRINTABLE ORGANIC ELECTRONICS, THROUGH 2017
Table 15 : GLOBAL MARKET FORECAST FOR MICROCHEMICAL SYSTEMS, THROUGH 2017
Table 16 : GLOBAL MARKET FORECAST FOR MICROCHEMICAL SENSORS, THROUGH 2017
Table 17 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC DRUG PUMPS, THROUGH 2017
Table 18 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC PROTEOMICS SYSTEMS, THROUGH 2017
Table 19 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC MEMS USED IN CBW SENSORS, THROUGH 2017
Table 20 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC DISPENSING DEVICES, THROUGH 2017
Table 21 : MICROFLUIDICS COMPANIES
Table 22 : SELECTED MICROFLUIDICS-RELATED DEALS, 1999-2011
Table 23 : COMPANIES AND INSTITUTIONS WITH THE GREATEST NUMBER OF NANOFLUIDICS-RELATED PATENTS, JAN. 1, 1999 THROUGH NOV. 30, 2012
 

List of Figures

Summary Figure : GLOBAL MARKET FOR MICROFLUIDIC TECHNOLOGIES, 2011–2017
Figure 1 : PASSIVE MICROFLUIDIC VALVE
Figure 2 : THE HYDROPHILIC EFFECT IN MICROFLUIDIC CONDUITS
Figure 3 : THE HYDROPHOBIC EFFECT IN MICROFLUIDIC CONDUITS
Figure 4 : GLOBAL MARKET FORECAST FOR MICROFLUIDIC TECHNOLOGIES, 2011–2017
Figure 5 : HTS/COMPOUND PROFILING COMPANIES, GLOBAL MARKET SHARE, 2011
Figure 6 : MICROFLUIDICS-BASED POC DIAGNOSTIC TEST MARKET SHARES, 2011
Figure 7 : GLOBAL MICROFLUIDIC INKJET MARKET SHARES, 2011
Figure 8 : IMPLANTABLE DRUG PUMP MARKET SHARES, 2011
Figure 9 : MICROFLUIDIC DEVICES FOR PROTEOMICS APPLICATIONS, MARKET SHARES, 2011
Figure 10 : PRINCIPLE OF EKPUMP
Figure 11 : SHARES OF U.S. PATENTS BY ASSIGNEE, JAN. 1, 1999 THROUGH NOV. 30, 2012
Figure 12 : SHARES OF PATENTS ISSUED BY EMPHASIS, JAN. 1, 1999 THROUGH NOV. 30, 2012