While there are a variety of industry test vehicles for the examination of materials compatibility, most available test boards leave something to be desired as there is often a dramatic difference in materials between such test boards and produced assemblies. A test vehicle was needed which could be used for both ion chromatography and SIR testing that would be more representative of mainstream manufacturing materials and processes. This document addresses the IPC-B-52 standard test vehicle which can be used to evaluate optimize a manufacturing process or to provide objective evidence that a chosen manufacturing material set and manufacturing process are compatible from a cleanliness standpoint. This user guideline has also been written as a companion document to the IPC-9202, providing clarification on what a manufacturer "should" do and what a manufacturer "must" do for demonstrating materials and process compatibility. 31 pages.